What is A Cryobank?

A cryobank, also known as a sperm bank, is a facility that collects, processes, stores, and distributes donated sperm for use in assisted reproductive technologies. Cryobanks play a crucial role in reproductive medicine by providing individuals and couples access to donor sperm when natural conception is not possible or advisable. Cryobanks operate under strict guidelines to ensure the safety and quality of the donated sperm.

The process begins with potential donors undergoing a thorough screening to assess their physical health, medical history, and genetic background. Once accepted as donors, they provide semen samples through masturbation or other collection methods. The samples are then processed to separate the sperm from different components of semen, such as seminal fluid. The processed sperm is then frozen and stored in liquid nitrogen tanks at extremely low temperatures to maintain viability.

What Services Are Typically Offered At A Cryobank?

Semen Analysis

Semen analysis is a laboratory test that examines the characteristics of semen, which is the fluid that contains sperm. It is typically one of the first tests conducted when assessing male fertility. During a semen analysis, several parameters are examined, including sperm count, motility (movement), morphology (shape), and volume of semen. These parameters provide valuable insights into the overall health and quality of sperm.

Semen analysis results can guide fertility treatment decisions. A fertility clinic may recommend different treatment options depending on the analysis findings. For example, if the sperm count is low, assisted reproductive techniques such as intrauterine insemination (IUI) or in vitro fertilization (IVF) may be suggested. On the other hand, if sperm motility is poor, intracytoplasmic sperm injection (ICSI) may be recommended.

Advancements in technology are continuously improving the accuracy and efficiency of semen analysis. For example, computer-assisted sperm analysis (CASA) systems provide more precise measurements of sperm parameters. Ongoing research also explores new ways to assess sperm quality, such as DNA fragmentation testing. These advancements hold promise for improving male fertility assessment and treatment options.

Cryobank Donor Sperm

The process of donor sperm banking involves several steps. First, potential donors undergo a thorough screening process to see if they meet the necessary health and genetic criteria. Once approved, donors provide a semen sample through masturbation or other cryobank-approved methods.

The collected sample is then processed in a laboratory to separate the sperm from other components of semen. The sperm is then mixed with a cryoprotectant solution to protect it during freezing. The sample is divided into vials and frozen using liquid nitrogen. The vials are then stored in a cryogenic tank at extremely low temperatures to maintain the viability of the sperm.

Cryobank facilities adhere to stringent quality control measures to ensure the safety and viability of their samples. When selecting a sperm donor, cryobanks provide various services to assist prospective parents in making informed decisions.

A diverse range of individuals and couples utilizes cryobanks. Some common reasons for using donor sperm include male infertility, genetic disorders, single parenthood by choice, same-sex couples, and couples where the male partner has undergone sterilization procedures.

For individuals or couples facing male infertility, cryobanks offer a solution by providing access to donor sperm. Donor sperm allows them to pursue assisted reproductive technologies such as in vitro fertilization (IVF) or intrauterine insemination (IUI) to achieve pregnancy.

In cases where there is a risk of passing on genetic disorders, using donor sperm can help mitigate that risk. Donors are thoroughly screened for genetic conditions, reducing the chances of passing on inherited diseases to future children.

Single individuals or same-sex couples also rely on sperm banks to fulfill their desire to have children. Sperm donation allows them to start or expand their families, regardless of marital status or sexual orientation.

Click here to view Cryobank America's donor qualifications and screening requirements, or click here to begin your donor search.

Chromosome Analysis

Chromosome analysis is a method of studying genetic makeup by examining the structure and number of chromosomes. This analysis can provide valuable insights into an individual's genetic potential and help identify potential genetic disorders. Chromosome analysis uses several techniques, including karyotyping, fluorescence in situ hybridization (FISH), and comparative genomic hybridization (CGH).

Karyotyping involves staining and examining chromosomes under a microscope to determine their structure and number. This technique can help identify missing or extra chromosomes and structural abnormalities such as translocations or deletions. FISH involves using fluorescent probes to label specific genes or regions of chromosomes, allowing for the detection of specific genetic abnormalities. CGH is a technique that compares the DNA from an individual to a reference DNA sample, allowing for the detection of copy number variations or changes in the number of copies of specific genes.

Chromosome analysis has been instrumental in identifying the genetic basis of inherited traits. Researchers have identified genes contributing to traits such as eye color, height, and intelligence by studying the structure and number of chromosomes. For example, the OCA2 gene on chromosome 15 is associated with the production of melanin, which determines eye color. Variations in this gene can result in different eye colors, such as blue or brown.

Similarly, studies have identified multiple genes on different chromosomes that determine height. These genes interact with each other and environmental factors to influence an individual's height. By studying the structure and number of chromosomes, researchers can better understand the complex genetic basis of traits.

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The Myriad Foresight Carrier Screening

The Myriad Foresight Carrier Screen is a cutting-edge genetic testing tool that provides comprehensive screening for over 175 genetic disorders. It utilizes advanced technology to analyze an individual's DNA and identify any mutations or variations that may indicate carrier status for a particular ailment. The Myriad Foresight Carrier Screen is highly accurate and reliable, providing individuals with valuable information about their genetic health.

One of the key advantages of the Myriad Foresight Carrier Screen is its comprehensive nature. It screens for genetic disorders, including those more prevalent in specific ethnic populations. This screening ensures that individuals receive a thorough assessment of their carrier status and can make informed decisions about their family planning options.

The Myriad Foresight Carrier Screen can detect carriers for various genetic disorders. Some specific conditions this screening can identify include cystic fibrosis, spinal muscular atrophy, sickle cell disease, and Tay-Sachs disease, among many others. These disorders vary in severity and prevalence, but all have the potential to impact an individual's health or the health of their future children.

By identifying carriers for these disorders, the Myriad Foresight Carrier Screen allows individuals to understand their risk of passing these conditions to their children. This knowledge can be invaluable in making informed decisions about family planning and taking proactive steps to safeguard the health of future generations.

Complete Bloodwork Testing

Complete bloodwork involves analyzing various components of your blood, including red blood cells, white blood cells, and platelets. Each component plays a crucial role in maintaining your overall health, and abnormalities in their levels can indicate underlying health conditions.

Red blood cells are responsible for carrying oxygen to all parts of your body. A complete blood count (CBC) measures the number of red blood cells in your blood. Abnormal levels of red blood cells can indicate anemia, which can be caused by a deficiency in iron, vitamin B12, or folic acid can cause. It can also indicate other underlying health conditions like kidney disease or bone marrow disorders.

White blood cells are essential to your immune system and help fight off infections and diseases. A CBC also measures the number of white blood cells in your blood. Elevated levels of white blood cells can indicate an infection or inflammation in your body. On the other hand, low levels of white blood cells can be a sign of a weakened immune system or certain medical conditions such as leukemia.

Platelets are responsible for clotting your blood to prevent excessive bleeding. A CBC also measures the number of platelets in your blood. Abnormal levels of platelets can indicate a bleeding disorder or a bone marrow disorder.

Cryobank Sperm Storage

Sperm storage is a critical aspect of cryobanks. Sperm can be stored in a cryobank for extended periods, allowing individuals or couples to use the sperm when they are ready to start a family.

The sperm storage process involves freezing the sperm samples in liquid nitrogen at extremely low temperatures. This freezing process helps preserve the viability of the sperm by slowing down cellular activity. Sperm can be stored in liquid nitrogen tanks for many years without significantly losing quality.

Cryobanks offer different storage options depending on individual needs and preferences. Some individuals may choose short-term storage if they plan to use the sperm within a few months or years. Others may opt for long-term storage to preserve their fertility for an extended period, such as cancer patients undergoing chemotherapy or radiation therapy.

The recommended storage duration for sperm varies depending on individual circumstances. Cryobanks can store sperm for several years without significant loss of quality. Still, it is important to consult with a fertility specialist to determine the best storage duration for your specific situation.

Known Donor Collection

Known sperm donor collection offers several benefits for families seeking to conceive through sperm donation. One of the main advantages is the potential for a stronger emotional connection and support system. When using a known sperm donor, there is the opportunity for ongoing communication and involvement between the donor, parents, and child. This involvement can create a sense of extended family and provide additional emotional support for all parties involved.

Additionally, having a known sperm donor can give families a sense of security and peace of mind. They can establish a relationship with the donor before conception, which can help build trust and ensure that the donor is a good fit for their family. Known donors are still required to undergo testing, which includes medical screening, blood testing, semen analysis, urinalysis, and more. They also have the option to receive additional screenings such as genetic testing or chromosome analysis.

Cryobank At-Home Insemination Kit

At-home insemination, also known as self-insemination, is a method used by individuals or couples trying to conceive without the assistance of a medical professional. It involves introducing sperm into the reproductive system to achieve pregnancy. Insertion is performed through various methods, such as using a sterile syringe or a cervical cap.

At-home insemination differs from other fertility treatments, such as in vitro fertilization (IVF) or intrauterine insemination (IUI) because it does not require medical intervention or fertility drugs. It is a more natural and less invasive method that individuals and couples can perform in the comfort of their own homes.

At Cryobank America, the process of at-home insemination is simple. Once you've chosen your perfect sperm donor, you'll place your vial order online. We'll schedule delivery of your vials around your schedule and fertility window. You'll receive our at-home insemination kit with everything you need to complete self-insemination. Click here for an in-depth overview of our process and steps for success.

Purchasing Donor Sperm

This is one question we get quite frequently. Where do I start?

This may seem like a confusing time, but ultimately you are wanting to start or grow your family, which will be an exciting milestone in your life!

To get started, we recommend contacting a fertility clinic to begin your journey. We have lots of recommendations and will be happy to guide you in the right direction.
Additionally, you have the option to do at-home insemination, and although we do not recommend this path, it is still an option, and we have seen success with vaginal insemination.

Prior to releasing any vials, either for clinic insemination or at-home insemination, you will need to have our Clinic Release Form completed by your physician. You can find that form HERE.

Once this form is completed and returned back to us, we can release the vials for both clinic and at-home insemination.

At-Home Insemination:

A Clinic Release form is only required for home insemination if you are shipping to the state of New York. In New York, a Clinic Release will need to be completed by a physician, nurse, or midwife.

Which vial should I use?

Currently, the majority of our donors have washed vials only. Washed vials are IUI-ready sperm samples. These samples have been processed for intrauterine insemination (IUI), but it is safe and effective to use them for IVF and vaginal insemination as well. Many of our recipients have reported pregnancies from IVF and vaginal insemination using IUI-ready samples.

You will want to purchase your vial(s) at least one week prior to your scheduled insemination. By planning ahead, you will ensure your vials are ready to use when you are ready to use them.

How much does it cost?

Here are some estimated costs of getting a sperm donor:
Donor Sperm: $649.00 IUI/ICI
Shipping: $200 for 1 vial 2+ vials: FREE (check to find current promo code)* | In-state shipping (outside of DFW): $75.00 | Dallas-Fort Worth area clinics: FREE
At-home insemination will have a $50 flat rate tank rental (7-days) or Free with 2+ vial purchase

Total Cost: $649-$849 per cycle using 1-IUI vial
$1298-$1498 for 2-IUI (washed) vials.

If you have any questions on how to purchase donor sperm, feel free to give us a call at 817-945-8708. You can live chat with one of our friendly representatives, and they will also be able to assist you.

What is CMV?

CMV stands for cytomegalovirus. It is a virus that can be transmitted to a developing fetus before birth. It is a member of the herpes family of viruses that include mono and chickenpox. The CDC states that nearly 1 in 3 children have already been infected with CMV by age 5, and by the age of 40, over half of the population is infected.

Primary CMV infection occurs in people who have never been exposed to the CMV virus before. Once a person becomes infected with CMV, the virus remains alive but dormant inside their body for the rest of their life. Recurrent CMV infection is when a dormant virus becomes active again. CMV infection is usually harmless and rarely causes illness. However, primary CMV infection can cause more severe problems for pregnant women than recurrent CMV infection.

CMV and Using a CMV Donor:

The FDA requires CMV testing on all men who intend to donate sperm. A positive result, however, doesn’t necessarily mean that a man will be ineligible to donate. Cryobank America will obtain semen samples from potential donors and then quarantine those specimens for at least six months. During that time, the man may have had CMV antibody levels tested several times. If the antibody tests indicate the possibility of a CMV infection close to the time of the sperm donation, the man will not be allowed to donate those specimens. If the testing is uncertain, those men will not be permitted to donate those specimens. However, if a donor tests positive for CMV IgG only, indicating a past infection, he will be allowed to contribute. These samples are labeled in the Cryobank America database as CMV-positive.

Recommendations:

A woman considering pregnancy with donor semen should have CMV antibody testing as part of their IDT. Those with a past infection are at low risk of transmitting CMV infection to a fetus and are at little to no risk if they decide to use a CMV-positive donor. Women never exposed to CMV should consider using a CMV-negative donor. Even though the risk from a CMV-positive donor is low, it is impossible to determine whether there will be a risk for infection.

For additional information on CMV, this link is especially helpful:

https://www.mayoclinic.org/diseases-conditions/cmv/symptoms-causes/syc-20355358

If you have any questions regarding CMV please contact us at [email protected] or at 817-945-8708 and we will be happy to help you out!