Donor Qualification

At Cryobank America, we are committed to providing the highest quality of sperm so you can build your happy, healthy family.

Rigorous Screening

Our donors undergo a rigorous background, personality, and behavioral screening by our staff physician and Licensed mental health professional so that we can provide you with the best options to build your family.
male with female doctor
Valerie Gelb

Valerie Gelb, our Medical Health Professional

Valerie Gelb graduated with a master’s degree in clinical psychology from Pepperdine University and is a licensed marriage and family therapist.

She has over 20 years of experience with assisted reproduction and specializes in psychological evaluations of egg donors, sperm donors, and gestational carrier candidates, as well as educational consultations for recipients of donor egg, sperm, and embryos.

Valerie is a member of the ASRM Mental Health Professionals Group, the Society for Ethics in Egg Donation and Surrogacy, and RESOLVE. She has focused her career on helping people navigate the path to parenthood.
Learn More about Valerie

Industry Exceeding Testing For Donor Qualification

All donors are subject to an extensive medical questionnaire and advanced genetic and infectious disease testing as required by the FDA, which, in most cases, exceeds the established standard. We continually endeavor to be the NEW Standard (in) Fertility.

Please contact us for more information on our donor qualification, screening, and testing.
Contact Us
had holding two vials
had holding two vials

Quality Sperm

At Cryobank America, we strive to maintain the industry’s highest standards for donor screening, testing, semen processing, and storage to provide quality, motile sperm. Our operations are fully licensed and inspected to ensure the best opportunity for a trustworthy and positive pregnancy in the future.

Each donor is identified through a biometric identification device and is compared to facial photographs, which are stored on-site to ensure proper proof of identity.

In addition to these quality assurance practices, Cryobank America leads the industry in providing the highest sperm counts per vial, increasing your chances of successful conception.

As a part of our commitment to helping you build your happy, healthy family, we offer the Conception Commitmentâ„¢ program.
Our Conception Commitmentâ„¢

Donor Screening

Infectious Disease Testing

Each donor must also complete an accompanying Medical Social Questionnaire (MSQ) with each Infectious Disease Testing (IDT). The IDT covers the following tests:

  • Chlamydia trachomatis (C. trachomatis)
  • Cytomegalovirus Antibodies (Total Antibody)
  • Cytomegalovirus Antibodies (IgM fraction)
  • HBV
  • Hepatitis B Surface Antigen (HBsAg)
  • Hepatitis B Core Antibody (HBcAb; HBc IgG-IgM)
  • Hepatitis C Virus Antibody (HCV)
  • HIV-1 / HCV / H / HBV NAT
  • Human Immunodeficiency Virus 1, O, and 2 (HIV 1/O/2)
  • Human T-Cell Lymphotropic Virus-I / II (HTLV-I / II)
  • Neisseria gonorrhea (N. gonorrhea)
  • Syphilis serology (Treponema pallidum)
  • West Nile Virus NAT

Non-Infectious Disease Testing

Non-infectious analyses are also performed on all Cryobank America Donors. The types of analyses in the blood chemistry profile include:

  • Albumin
  • Alkaline Phosphatase
  • Alanine Aminotransferase (ALT)
  • Aspartate Aminotransferase (AST)
  • Calcium
  • Cholesterol (HDL, LDL, VLDL)
  • Creatinine
  • Glucose
  • Lactate Dehydrogenase (LDH)
  • Iron (Total Fe, Fe Binding, % Saturation)
  • Triglycerides
  • Total Bilirubin
  • Total Protein
  • Urea Nitrogen
  • Uric Acid

Complete Blood Count

The following parameters are evaluated in the Completed Blood Count:

  • Cell morphology
  • Hematocrit
  • Hemoglobin
  • Mean Corpuscular Hemoglobin (MCH)
  • Mean Corpuscular Hemoglobin Concentration (MCHC)
  • Mean Corpuscular Volume (MCV)
  • Mean Platelet Volume (MPV)
  • Microscopic examination of Basos
  • Eos
  • Lymphs
  • Polys
  • Red Blood
  • Platelet Screen
  • Red Blood Cell (RBC) Count
  • White Blood Cell (WBC) Count

Urinalysis

CA Donors will also undergo routine urinalyses, which is used to screen for the general health of a donor’s urinary tract system.

The following parameters are evaluated with the urinalysis:

  • Bilirubin
  • Clarity
  • Color
  • Glucose
  • Ketones
  • Leukocyte esterase
  • pH
  • Protein
  • Microscopic evaluation for squamous cells
  • Casts
  • Crystals

Drug Testing and Criminal History Background Check

Drug use has been known to affect the potency of motile sperm. Therefore, in addition to the testing performed above, Cryobank America performs criminal background checks and drug testing on all donors to provide the highest quality products to our clients.

Psychological Evaluation (a Cryobank America Exclusive!)

As part of joining the Cryobank America Sperm Donor Program, each donor must meet with a licensed mental health professional and undergo a psychological evaluation that includes a clinical interview to assess for current and past psychological concerns.

Chromosome Analysis

Chromosome Analysis (also known as Karyotyping) is used to detect chromosome abnormalities, which can help uncover hidden genetic diseases, birth defects, blood disorders, and lymphatic system disorders. All Cryobank America donors undergo Chromosome Analysis testing.

Myriad Women's Health
Genetic Screening

Every Cryobank America donor will have genetic carrier screening performed by Myriad Women's Health, a CLIA-regulated testing facility. As of 7/22/2024, all donors have been tested by Myriad Foresight Carrier Screen of 266 genetic conditions. Any donor's previous to 7/22/2024 have been tested by Myriad Foresight Carrier Screen of 175 genetic conditions. Any condition with the sperm icon next to it, indicates screening that is included in the 266 condition panel.

A

  • 3-methylcrotonyl-CoA Carboxylase Deficiency, MCC2-related   
  • 6-pyruvoyl-tetrahydropterin Synthase Deficiency 
  • Abetalipoproteinemia   
  • Achromatopsia, CNGB3-related   
  • Acute Liver Failure, TRMU-related   
  • Adenosine Deaminase Deficiency  
  • Aicardi-Goutières Syndrome   
  • Aldosterone Synthase Deficiency   
  • Alkaptonuria   
  • Alpha Thalassemia, HBA1/HBA2-related 
  • Alpha-1 Antitrypsin Deficiency 
  • Alpha-mannosidosis 
  • Alpha-sarcoglycanopathy 
  • Alport Syndrome, COL4A3-related 
  • Alport Syndrome, COL4A4-related 
  • Alstrom Syndrome 
  • Andermann Syndrome 
  • Argininemia 
  • Argininosuccinic Aciduria 
  • Arthrogryposis, Impaired Intellectual Development, and Seizures   
  • ARX-related Disorders   
  • Asparagine Synthetase Deficiency  
  • Aspartylglucosaminuria 
  • Ataxia with Vitamin E Deficiency  
  • Ataxia-telangiectasia 
  • ATP7A-related Disorders 
  • Atransferrinemia   
  • Autoimmune Polyglandular Syndrome Type 1 
  • Autosomal Recessive Osteopetrosis Type 1 
  • Autosomal Recessive Polycystic Kidney Disease, PKHD1-related 
  • Autosomal Recessive Spastic Ataxia of Charlevoix-Saguenay 

B

  • Bardet-Biedl Syndrome, BBS1-related 
  • Bardet-Biedl Syndrome, BBS10-related 
  • Bardet-Biedl Syndrome, BBS12-related 
  • Bardet-Biedl Syndrome, BBS2-related 
  • BCS1L-related Disorders 
  • Beta Globin-related Hemoglobinopathy (Including Beta Thalassemia and Sickle Cell Disease) 
  • Beta-ketothiolase Deficiency   
  • Beta-sarcoglycanopathy 
  • Biotin-thiamine–responsive Basal Ganglia Disease  
  • Biotinidase Deficiency  
  • Bloom Syndrome 

C

  • Calpainopathy 
  • Canavan Disease 
  • Carbamoylphosphate Synthetase I Deficiency 
  • Carnitine Palmitoyltransferase IA Deficiency 
  • Carnitine Palmitoyltransferase II Deficiency 
  • Cartilage-hair Hypoplasia 
  • CC2D2A-related Disorders -  
  • CEP290-related Disorders  
  • Cerebrotendinous Xanthomatosis 
  • Chronic Granulomatous Disease, CYBA-related  
  • Citrullinemia Type 1 - 
  • Classical-like Ehlers-Danlos Syndrome, TNXB-related  
  • CLN3-related Disorders 
  • CLN5-related Neuronal Ceroid Lipofuscinosis 
  • CLN8-related Neuronal Ceroid Lipofuscinosis 
  • Cohen Syndrome 
  • Combined Pituitary Hormone Deficiency, PROP1-related 
  • Congenital Adrenal Hyperplasia, CYP11A1-related  
  • Congenital Adrenal Hyperplasia, CYP11B1-related - 
  • Congenital Adrenal Hyperplasia, CYP21A2-related 
  • Congenital Amegakaryocytic Thrombocytopenia  
  • Congenital Disorder of Glycosylation Type Ic 
  • Congenital Disorder of Glycosylation, MPI-related 
  • Congenital Disorder of Glycosylation, PMM2-related 
  • Congenital Hydrocephalus, CCDC88C-related  
  • Congenital Insensitivity to Pain with Anhidrosis, NTRK1-related -  
  • Congenital Myasthenic Syndrome, CHRNE-related  
  • Costeff Optic Atrophy Syndrome - Gene 
  • Creatine Transporter Deficiency   
  • Cystic Fibrosis 
  • Cystinosis

D-F

  • D-bifunctional Protein Deficiency 
  • Delta-sarcoglycanopathy 
  • Dihydrolipoamide Dehydrogenase Deficiency 
  • Dihydropyrimidine Dehydrogenase Deficiency  
  • Distal Renal Tubular Acidosis with Deafness, ATP6V1B1-related  
  • Donnai–Barrow Syndrome  
  • DYNC2H1-related Disorders  
  • Dysferlinopathy 
  • Dystrophic Epidermolysis Bullosa  
  • Dystrophinopathy (Including Duchenne/Becker Muscular Dystrophy) 
  • Ehlers-Danlos Syndrome, ADAMTS2-related  
  • Enhanced S-cone Syndrome  
  • ERCC2-related Disorders  
  • ERCC6-related Disorders 
  • ERCC8-related Disorders 
  • EVC-related Ellis-van Creveld Syndrome 
  • EVC2-related Ellis-van Creveld Syndrome 
  • Fabry Disease 
  • Factor XI Deficiency  
  • Familial Dysautonomia 
  • Familial Hemophagocytic Lymphohistiocytosis, PRF1-related -  
  • Familial Hyperinsulinism, ABCC8-related 
  • Familial Hyperinsulinism, KCNJ11-related - 
  • Familial Mediterranean Fever - 
  • Fanconi Anemia Complementation Group A 
  • Fanconi Anemia, FANCC-related 
  • FKRP-related Disorders 
  • FKTN-related Disorders 
  • Fragile XE Syndrome  
  • Fraser Syndrome, GRIP1-related  
  • Free Sialic Acid Storage Disorders

G-H

  • Galactokinase Deficiency 
  • Galactosemia 
  • Gamma-sarcoglycanopathy 
  • Gaucher Disease 
  • GJB2-related DFNB1 Nonsyndromic Hearing Loss and Deafness - 
  • GLB1-related Disorders - 
  • Glucose-6-phosphate Dehydrogenase Deficiency  
  • Glutaric Acidemia, GCDH-related 
  • Glycine Encephalopathy, AMT-related 
  • Glycine Encephalopathy, GLDC-related - 
  • Glycogen Storage Disease Type Ia 
  • Glycogen Storage Disease Type Ib 
  • Glycogen Storage Disease Type III - 
  • Glycogen Storage Disease, GBE1-related  
  • Glycogen Storage Disease, PFKM-related  
  • Glycogen Storage Disease, PYGM-related  
  • GNE Myopathy - 
  • GNPTAB-related Disorders 
  • HADHA-related Disorders - 
  • Hearing Loss and Deafness, LOXHD1-related  
  • Hemophilia B  
  • Hereditary Fructose Intolerance 
  • Hermansky-Pudlak Syndrome, HPS1-related  
  • Hermansky-Pudlak Syndrome, HPS3-related  
  • Hexosaminidase A Deficiency (Including Tay-Sachs Disease) 
  • HMG-CoA Lyase Deficiency 
  • Holocarboxylase Synthetase Deficiency 
  • Homocystinuria, CBS-related 
  • Homocystinuria, MTHFR-related  
  • Hydrolethalus Syndrome 
  • Hypophosphatasia

I-L

  • Inherited Retinal Dystrophy, RPE65-related  
  • Isovaleric Acidemia 
  • Joubert Syndrome 2 
  • Joubert Syndrome, AHI1-related  
  • Junctional Epidermolysis Bullosa, LAMA3-related 
  • Junctional Epidermolysis Bullosa, LAMB3-related - 
  • Junctional Epidermolysis Bullosa, LAMC2-related 
  • Krabbe Disease 
  • L1 Syndrome  
  • Leigh Syndrome, French-Canadian Type 
  • Lipoid Congenital Adrenal Hyperplasia 
  • Lysosomal Acid Lipase Deficiency 

M

  • Maple Syrup Urine Disease Type Ia 
  • Maple Syrup Urine Disease Type Ib - 
  • Maple Syrup Urine Disease Type II - 
  • Medium-chain Acyl-CoA Dehydrogenase Deficiency 
  • Megalencephalic Leukoencephalopathy with Subcortical Cysts 
  • Metachromatic Leukodystrophy 
  • Methylmalonic Acidemia, cblA Type 
  • Methylmalonic Acidemia, cblB Type - 
  • Methylmalonic Acidemia, MMUT-related - 
  • Methylmalonic Aciduria and Homocystinuria, cblC Type - 
  • Mevalonate Kinase Deficiency  
  • Microcephaly with Seizures and Brain Atrophy, MED17-related -  
  • Microphthalmia, Anophthalmia, and Coloboma, VSX2-related -  
  • Mitochondrial Complex I Deficiency, NDUFAF5-related  
  • Mitochondrial Complex I Deficiency, NDUFS4-related -  
  • Mitochondrial Complex I Deficiency, NDUFS6-related  
  • Mitochondrial Complex IV Deficiency, SCO2-related  
  • Mitochondrial Neurogastrointestinal Encephalopathy Disease  
  • MKS1-related Disorders - 
  • Mucolipidosis III Gamma 
  • Mucolipidosis IV 
  • Mucopolysaccharidosis Type I 
  • Mucopolysaccharidosis Type II 
  • Mucopolysaccharidosis Type IIIA 
  • Mucopolysaccharidosis Type IIIB 
  • Mucopolysaccharidosis Type IIIC - 
  • Multiple Sulfatase Deficiency  
  • Muscular Dystrophy, LAMA2-related - 
  • MYO7A-related Disorders 
  • Myopathy, Lactic Acidosis, and Sideroblastic Anemia 1  
  • Myotonia Congenita -  

N-O

  • NAGA-related Disorders  
  • NEB-related Nemaline Myopathy 
  • Nephrotic Syndrome, NPHS1-related 
  • Nephrotic Syndrome, NPHS2-related 
  • Neuronal Ceroid Lipofuscinosis, CLN6-related 
  • Neuronal Ceroid Lipofuscinosis, PPT1-related 
  • Niemann-Pick Disease Type C1 
  • Niemann-Pick Disease Type C2 
  • Niemann-Pick Disease, SMPD1-related 
  • Nijmegen Breakage Syndrome 
  • Normophosphatemic Familial Tumoral Calcinosis  
  • Oculocutaneous Albinism, OCA2-related  
  • Oculocutaneous Albinism, TYR-related  
  • Opitz G/BBB Syndrome, MID1-related  
  • Ornithine Aminotransferase Deficiency  
  • Ornithine Transcarbamylase Deficiency - 

P-R

  • PCCA-related Propionic Acidemia 
  • PCCB-related Propionic Acidemia 
  • PCDH15-related Disorders - 
  • Pendred Syndrome 
  • Peroxisome Biogenesis Disorder Type 1 
  • Peroxisome Biogenesis Disorder Type 3 
  • Peroxisome Biogenesis Disorder Type 4 - 
  • Peroxisome Biogenesis Disorder Type 5 
  • Peroxisome Biogenesis Disorder Type 6 - 
  • Phenylalanine Hydroxylase Deficiency 
  • PLP1-related Disorders  
  • POLG-related Disorders  
  • POMGNT-related Disorders 
  • Pompe Disease 
  • Pontocerebellar Hypoplasia, RARS2-related -  
  • Pontocerebellar Hypoplasia, SEPSECS-related  
  • Pontocerebellar Hypoplasia, VPS53-related -  
  • Pontocerebellar Hypoplasia, VRK1-related  
  • Primary Carnitine Deficiency 
  • Primary Ciliary Dyskinesia, DNAH5-related  
  • Primary Ciliary Dyskinesia, DNAI1-related -  
  • Primary Ciliary Dyskinesia, DNAI2-related -  
  • Primary Hyperoxaluria Type 1 - 
  • Primary Hyperoxaluria Type 2 
  • Primary Hyperoxaluria Type 3 
  • Primary Microcephaly, MCPH1-related  
  • Primary Trimethylaminuria  
  • Pseudocholinesterase Deficiency  
  • Pycnodysostosis 
  • Pyruvate Carboxylase Deficiency 
  • RAPSN-related Disorders -  
  • Refsum Disease, PHYH-related  
  • Retinitis Pigmentosa, CERKL-related  
  • Retinitis Pigmentosa, DHDDS-related  
  • Retinitis Pigmentosa, EYS-related  
  • Retinitis Pigmentosa, FAM161A-related -  
  • Rhizomelic Chondrodysplasia Punctata Type 1 
  • RTEL1-related Disorders - 

S-U

  • Sandhoff Disease 
  • Serine Deficiency Disorder, PHGDH-related -  
  • Severe Combined Immunodeficiency, RAG2-related  
  • Short-chain Acyl-CoA Dehydrogenase Deficiency 
  • Sjogren-Larsson Syndrome 
  • SLC26A2-related Disorders 
  • Smith-Lemli-Opitz Syndrome 
  • Spastic Paraplegia Type 15 
  • Spastic Paraplegia, TECPR2-related  
  • Spinal Muscular Atrophy 
  • Spinocerebellar Ataxia, ANO10-related -  
  • Spondylothoracic Dysostosis 
  • Surfactant Deficiency, ABCA3-related -  
  • TGM1-related Autosomal Recessive Congenital Ichthyosis 
  • TPP1-related Neuronal Ceroid Lipofuscinosis 
  • Tyrosine Hydroxylase Deficiency 
  • Tyrosinemia Type I 
  • Tyrosinemia Type II 
  • USH1C-related Disorders 
  • USH2A-related Disorders 
  • Usher Syndrome Type 3 

V-X

  • Very-long-chain Acyl-CoA Dehydrogenase Deficiency 
  • Vitamin D–dependent Rickets, CYP27B1-related  
  • VPS13A Disease -  
  • Wilson Disease 
  • X-linked Adrenal Hypoplasia Congenita 
  • X-linked Adrenoleukodystrophy - 
  • X-linked Alport Syndrome 
  • X-linked Choroideremia  
  • X-linked Juvenile Retinoschisis 
  • X-linked Myotubular Myopathy 
  • X-linked Retinal Dystrophy, RPGR-related  
  • X-linked Severe Combined Immunodeficiency 
  • Xeroderma Pigmentosum Group A - 
  • Xeroderma Pigmentosum Group C 

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